ANCIENT WISDOM
ANCIENT WISDOM
MODERN SCIENCE
MODERN SCIENCE

ANCIENT WISDOM

BIRCH POLYPORE

(Fomitopsis betulina)

A Versatile Medicinal Mushroom - the Birch Polypore is a distinctive bracket fungus that thrives exclusively on birch trees, playing a crucial role in natural forest ecosystems. Recognized for its smooth, pale brown cap and white underside, this mushroom has been valued for centuries in traditional medicine.

Birch Polypore is best known for its powerful antimicrobial, antifungal, and immune-boosting properties. It contains betulinic acid, a compound derived from birch trees, which is studied for its potential anti-cancer, anti-inflammatory, and antiviral effects. Traditionally, it has been used to support gut health, combat infections, and even as a natural wound dressing due to its antibacterial qualities.

Today, Birch Polypore is also often used to support immunity, digestion, and overall wellness. Some biohackers explore its potential for cognitive support and stress resilience, making it a fascinating addition to the growing world of functional mushrooms.

LEGEND & FOLKLORE

Known as the resiliant “Survival Fungus".

The most famous legend is with Ötzi the Iceman, a 5,300-year-old mummy discovered in the Alps. Among his belongings was a pouch containing this very fungus, suggesting that prehistoric people used it as a medicinal ally against parasites and wounds.

In Norse mythology it was believed to be a warrior’s fungus, used by Viking berserkers to cleanse wounds and fortify the spirit.

Among the Slavic and Siberian shamans, Birch Polypore was known as the “Whispering Fungus”, a conduit between the spirit world and the living. It was burned during rituals to enhance dreams and divination.

Cunning European folk and herbalists regarded Birch Polypore as a fungal amulet against disease and dark magic. Hung in doorways or worn as a dried pendant, it was believed to ward off evil spirits.

MODERN SCIENCE

SCIENCE INFORMATION REVIEW

BIRCH POLYPORE

(Fomitopsis betulina)

Welcome to the Fung Shui Birch Polypore scientific research page which connects you to our ever evolving library of research and peer-reviewed papers. Where a reference is provided, you can find the corresponding number in the research references towards the bottom of the page in the 'peer reviewed papers & articles' section.

Fomitopsis betulina exhibits a wide range of health-promoting properties, including antimicrobial, antiparasitic, antiviral, anti-inflammatory, anticancer, immunomodulatory, antioxidant, neuroprotective, antidiabetic, and gastrointestinal benefits. While traditional uses are supported by emerging scientific evidence, further research, including clinical trials, is necessary to fully understand and validate these health benefits.

INFECTIONS & WOUND HEALING

Birch polypore has demonstrated significant antimicrobial activity, particularly against Gram-positive bacteria such as Staphylococcus aureus and Enterococcus faecalis and even multi-drug-resistant bacteria. This is attributed to antibiotic compounds like piptamine, which exhibit strong antibacterial effects. Traditionally, fresh fruiting bodies were used to create antiseptic and anti-bleeding dressings. [1][4][5][6]

VIRAL INFECTIONS

Research indicates that birch polypore, rich in pentacyclic triterpenes such as betulinic acid, exhibits notable antiviral properties. Studies have shown its potential against various viruses, including influenza, poxvirus and yellow fever, by inhibiting viral replication. One study showed birch polypore to block HIV replication. Extracts shielded fibroblasts from vaccina virus, lethal encephalitis and herpes. [2]

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ANTI-INFLAMMATORY

The triterpenoid compounds (polyporenic acids) found in birch polypore have been shown to possess anti-inflammatory effects. These compounds can modulate the body’s inflammatory response, making the fungus potentially beneficial for conditions characterized by inflammation. [1]

These effects align with its traditional use as a 'wound herb' to reduce pain and swelling. An ethanol extract also downregulated inflammatory pathways in cultured cells. [4]

By curbing enzymes and mediators that drive inflammation, birch polypore aids healing.

GASTROINTESTINAL SUPPORT (GUT HEALTH)

Traditionally, birch polypore has been used to address various gastrointestinal disorders. Its antimicrobial and anti-inflammatory properties may contribute to maintaining gut health and alleviating digestive issues. [1] The same properties are said to sooth gastric mucosa and contribute to protection from ulcers. It has a mild purgative effect which could help expel intestinal parasites and relieve constipation. [8]

Also rich in polysaccharides (like glucans) that may act as prebiotics, nourishing beneficial gut bacteria. Medicinal mushrooms in general are known to improve gut flora balance. [7]

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ANTICANCER POTENTIAL

Birch polypore has been studied (preclinical) for its anticancer properties. Extracts from the fungus have demonstrated cytotoxic effects to inhibit tumor cell proliferation, reduce cell motility, and induce morphological changes in cancer cells. A broad range of cancer cell lines have been shown to improve including Lung, colon, breast, brain and cervical cancers. Notably, these effects were observed with minimal toxicity to normal cells. [3] The active constituents induce apoptosis (programmed cell death) in tumor cells and inhibit their proliferation by blocking tumor cell signaling pathways.[5]

Compounds like betulinic acid (concentrated from birch bark by the fungus) show selective toxicity to melanoma and other tumor cells. Moreover, birch polypore extracts suppress cancer cell migration and invasion by downregulating matrix-degrading enzymes (MMPs) . While human clinical studies are lacking, these in vitro and animal findings suggest birch polypore as a promising source of anticancer agents. [1][4]

NEUROPROTECTIVE PROPERTIES (BRAIN)

Preliminary studies suggest that birch polypore may have neuroprotective effects. Compounds within the fungus could potentially protect nerve cells from damage, maintain neurotransmitter levels and memory, offering avenues into treatment for neurodegenerative conditions such as alzheimers. [1]

F. Betulina's anti inflammatory properties may also reduce neuronal oxidative stress and neuroinflammation. Birch polypore's ability to inhibit enzymes implicated in dementia and to guard against cellular stress suggests a promising role in sustaining neural health and function. [5]

IMMUNE SYSTEM SUPPORT

Like many medicinal mushrooms, birch polypore is valued for its immunomodulatory effects. Its cell wall polysaccharides (glucans) can stimulate the immune system. Water extracts of F. betulina have been shown to activate white blood cells. One study demonstrated that extracts triggered human neutrophils to produce reactive oxygen species, an important part of the immune response to destroy microbes.[7]

F. betulina preparations have also increased cytokine activity and macrophage function.[1]

Additionally, the mushroom contains a D-glucan, which has been used to induce enzymes that break down harmful biofilms.[7]

By priming innate immunity and possibly enhancing adaptive responses, birch polypore acts as an immune tonic. These properties support its use for preventing infections and as an adjuvant in therapies (though clinical validation is needed). [1]

DIABETES HELP (BLOOD SUGAR REGULATION)

Emerging evidence indicates F. betulina may aid in glucose metabolism and diabetes management. While specific studies on birch polypore in diabetics are limited, its bioactive components suggest antidiabetic potential. The fungus produces various triterpenoids (lanostane derivatives) similar to those in other Fomitopsis species that improve insulin signaling. For example, lanostane compounds from the related F. pinicola can inhibit protein tyrosine phosphatase 1B (PTP1B) and enhance glucose uptake in cells, mechanisms that lower blood sugar.[9]

Polysaccharides from medicinal mushrooms are known to reduce insulin resistance and blood glucose by modulating key metabolic enzymes and transporters (e.g. lowering GSK-3β activity and increasing GLUT4).[10]

Additionally, F. betulina’s antioxidants and anti-inflammatory effects may protect pancreatic beta-cells from oxidative damage, indirectly supporting insulin secretion. Although direct clinical trials are lacking, the mushroom’s metabolites show promise for improving glycemic control and mitigating complications of diabetes, warranting further research. [1]

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ANTIPARASITIC EFFECTS

F. betulina contains agaric acid, a compound toxic to parasitic worms such as Trichuris trichiura (whipworm). This antiparasitic property is believed to be one reason why Ötzi the Iceman (who was found to have whipworm) carried birch polypore, using it to combat intestinal parasites. [1] In addition ergosterol peroxied from its fruiting body has shown activity against malaria parasites.[7]

OXIDATIVE STRESS & CELLULAR HEALTH

The fungus exhibits rich antioxidant properties such as vitamins (C, E, Beta Carotene) and phenolic compounds, which scavenge free radicals in the body. By reducing oxidative stress, birch polypore that may contribute to cellular health and protect against various diseases associated with free radical damage, indicating potent antioxidant effects. [1]

Additionally, birch polypore’s inhibition of enzymes like hyaluronidase helps prevent the breakdown of extracellular matrix, thereby reducing tissue damage during inflammation. [4]

By lowering oxidative stress and stabilizing cellular environments, F. betulina may help mitigate chronic diseases linked to oxidative damage and ageing.

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DISCLAIMER

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This website has not yet been reviewed by UK MHRA and should not replace medical care so please check with your healthcare professional. Food supplements should not be used as a substitute for a varied and balanced diet and a healthy lifestyle. Our tinctures are not intended to diagnose, treat, cure or prevent any diseases. Fung Shui nor nor any of its affiliated companies accept neither liability nor responsibilty to any any person with respect to loss, injury or damage caused, or alleged to be caused, directly or indirectly by the information contained in advertisments, this website or product labelling.

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